Randomized placebo-controlled phase 2 trial of a Lactobacillus crispatus probiotic given intravaginally for prevention of recurrent urinary tract infection.

by Osel | Apr 14, 2011 | LACTIN-V CLINICAL

Stapelton, AE, Au-Yeung, M, Hooton, TM, Frederick, DN, Roberts, PL, Czaja, CA, Yarova-Yarovaya, Y, Fiedler, T, Cox, M and Stamm, WE. Clin Infect Dis. 2011 May;52(10):1212-7. doi: 10.1093/cid/cir183. Epub 2011 Apr 14.     Synopsis: LACTIN-V was tested in a...

Inhibition of the cytotoxic effect of Clostridium difficile in vitro by Clostridium butyricum MIYAIRI 588 strain.

by Osel | Jan 23, 2011 | CBM588

Woo TD, Oka K, Takahashi M, Hojo F, Osaki T, Hanawa T, Kurata S, Yonezawa H, Kamiya S. J Med Microbiol. 2011 Nov;60(Pt 11):1617-25. doi: 10.1099/jmm.0.033423-0. Epub 2011 Jun 23.     Synopsis: This study investigated the inhibitory interaction between...

Phase 2a study assessing colonization efficiency, safety and acceptability of Lactobacillus crispatus CTV-05 for the prevention of bacterial vaginosis.

by Osel | Dec 1, 2010 | LACTIN-V CLINICAL

Hemmerling, A, Harrison, W, Schroeder, A, Park, J, Korn, A, Shiboski, S, Foster-Rosales, A., and Cohen, CR. Sex Transm Dis. 2010 Dec;37(12):745-50. doi: 10.1097/OLQ.0b013e3181e50026.     Synopsis: LACTIN-V was tested in a randomized, blinded,...

Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers.

by Osel | Jul 1, 2010 | MUCOCEPT

Vangelista, L, Secchi, M, Liu, X, Bachi, A, Xu, Q, Lusso, P. Antimicrob Agents Chemother. 2010 Jul;54(7):2994-3001. doi: 10.1128/AAC.01492-09. Epub 2010 May 17.     Synopsis: Proof of concept for the use of Lactobacillus jensenii-produced C1C5 RANTES to...

The superior folding of a RANTES analogue expressed in lactobacilli as compared to mammalian cells reveals a promising system to screen new RANTES mutants.

by Osel | Nov 1, 2009 | MUCOCEPT

Secchi, M, Xu, Q, Lusso, P, and Vangelista, L. Protein Expr Purif. 2009 Nov;68(1):34-41. doi: 10.1016/j.pep.2009.06.018. Epub 2009 Jun 30.     Synopsis: RANTES is a natural protein expressed on activated T cells; one of the activities of RANTES is to bind to...