Hemmerling, A, Harrison, W, Schroeder, A, Park, J, Korn, A, Shiboski, S, Foster-Rosales, A., and Cohen, CR. Sex Transm Dis. 2010 Dec;37(12):745-50. doi: 10.1097/OLQ.0b013e3181e50026.
Synopsis: LACTIN-V was tested in a randomized, blinded, placebo-controlled study of 24 women treated for bacterial vaginosis with metronidazole. Overall, 61% of women in the LACTIN-V group were colonized with L. crispatus CTV-05 on the Day 10 or Day 28 follow up visits. Among LACTIN-V users with complete adherence to the study regimen, 78% were colonized. The LACTIN-V strain colonized well, and was safe, well-tolerated and acceptable in women treated for BV.